Total Publications: 102 Total Citations: 6443 H-Index: 44
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2025
102. Brix, K.V., J. Baker, A. de Bruyn, J. Ings, C. Good, M.C. Arnold, and J. Elphick. 2025. Effects of maternally transferred egg selenium on embryo-larval survival, growth, and development in mountain whitefish (Prosopium williamsoni). Environ. Toxicol. Chem. In Press. PDF Supplemental Tables S1-S3 Supplemental Table S4
101. Detering, C.A., K.V. Brix, M. Adzic, B.A. Fulton, and D.K. DeForest. 2025. Relationships in selenium concentrations among fish tissues to support selenium assessments and regulations. Environ. Toxicol. Chem. 44(6): 1742-1757. PDF
100. Brix, K.V., L.M. Tear, J. Elphick, J. Ings, C. Detering, M. Carr, K. Raes, M.C. Arnold, M. Adzic, M. Hecker, A. de Bruyn, and D.K. DeForest. 2025. Oocyte developmental stage influences ovary selenium concentrations in fish – implications for ovary selenium monitoring. Environ. Toxicol. Chem. 44(6): 1561-1574. PDF
99. de Bruyn, A.M.H., C.B. Heddle, J. Ings, H. Gurleyuk, K.V. Brix, S.N. Luoma, and M.C. Arnold. 2025. Development of a bioaccumulation model for selenium oxyanions and organoselenium in stream biota. Environ. Toxicol. Chem. 44(2): 363-374. PDF
2024
98. Mentzel, S., R. Nathan, P. Noyes, K.V. Brix, S.J. Moe, J.R. Rohr, J. Verheyen, P.J. van den Brink, and J. Stauber. 2024. Evaluating the effects of climate change and chemical, physical, and biological stressors on nearshore coral reefs: A case study in the Great Barrier Reef, Australia. Integr. Environ. Assess. Manag. 20(2): 401-418. PDF
97. Moe, S.J., K.V. Brix, W.G. Landis, J.L. Stauber, J.F. Carriger, J.D. Hader, T. Kunimitsu, S. Mentzel, R. Nathan, P.D. Noyes, R. Oldenkamp, J.R. Rohr, P.J. van den Brink, J. Verheyen, and R.E. Benestad. 2024. Integrating climate model projections into environmental risk assessment: A probabilistic modeling approach. Integr. Environ. Assess. Manage. 20(2): 367-383. PDF
96. Stahl, R.G., A.B.A. Boxall, K.V. Brix, W.G. Landis, J.L. Stauber, and S.J. Moe. 2024. Incorporating climate change model projections into ecological risk assessments to help inform risk management and adaptation strategies: Synthesis of a SETAC Pellston Workshop. Integr. Environ. Assess. Manag. 20(2): 359-366. PDF
2023
95. Brix, K.V., S. Baken, C.A. Poland, R. Blust, L.J. Pope, and C.R. Tyler. 2023. Challenges and recommendations in assessing potential endocrine-disrupting properties of metals in aquatic organisms. Environ. Toxicol. Chem. 42(12): 2564-2579. PDF
94. de Bruyn, A.M.H., B.P. Lo, J. Van Geest, D. Semeniuk, J.R. Elphick, J. Ings, C. Good, M.C. Arnold, and K.V. Brix. Maternal transfer and effects of selenium on early life stage development of redside shiner (Richardsonius balteatus). 42(11): 2350-2357. PDF
93. Brix, K.V., L. Tear, D.K. DeForest, and W.J. Adams. 2023. Development of multiple linear regression models for predicting chronic iron toxicity to aquatic organisms. Environ. Toxicol. Chem. 42(6): 1386-1400. PDF
92. DeForest, D.K., A.C. Ryan, L.M. Tear, and K.V. Brix. 2023. Comparison of multiple linear regression models for predicting acute and chronic zinc toxicity to freshwater organisms. Environ. Toxicol. Chem. 42(2): 393-413. PDF
91. Brix, K.V., R. Blust, J. Mertens, S. Baken, E.T. Middleton, and C. Cooper. 2023. Evaluation of effects-based methods as monitoring tools for assessing ecological impacts of metals in aquatic ecosystems. Integr. Environ. Monitor. Assess. PDF
2022
90. Cremazy, A., S. Braz-Mota, K.V. Brix, R.M. Duarte, A.L. Val, and C.M. Wood. 2022. Investigating the mechanisms of dissolved organic matter protection against copper toxicity in fish of Amazon’s black waters. Sci. Tot. Environ. 843: 157032. PDF
89. Brix, K.V., G. De Boeck, S. Baken, and D.J. Fort. 2022. Adverse outcome pathways for chronic copper toxicity to fish and amphibians. Environ. Toxicol. Chem. 41(12): 2911-2927. PDF
2021
88. Brix, K.V., L.M. Tear, R.C. Santore, K. Croteau, and D.K. DeForest. 2021. Comparative performance of multiple linear regression and biotic ligand models for estimating the bioavailability of copper in freshwater. Environ. Toxicol. Chem. 40(6): 1649-1661. PDF
87. Brix, K.V., J. Baker, W. Morris, K. Ferry, C. Pettem, J. Elphick, L.M. Tear, R. Napier, M. Adzic, and D.K. DeForest. 2021. Effect of maternally transferred egg selenium on embryo-larval survival, growth and development in Arctic Grayling (Thymallus arcticus). Environ. Toxic. Chem. 40(2): 380-389. PDF
2020
86. Cremazy, A., K.V. Brix, D.S. Smith, W. Chen, M. Grosell, C.E. Schlekat, E.R. Garman, and C.M. Wood. 2020. A mystery tale: Nickel is fickle when snails fail, investigating the variability in the great pond snail Ni sensitivity. Integr. Environ. Manage. Assess. 16(6): 983-997. PDF
85. Jung, E.H., K.V. Brix, J.G. Richards, A.L. Val, and C.J. Brauner. 2020. Thermal and hypoxia tolerance are correlated in Amazon fishes: implication for warming. Sci. Tot. Environ. 748: 141349. PDF
84. DeForest, D.K., K.V. Brix, L.M. Tear, A.S. Cardwell, W.A. Stubblefield, E. Nordheim, and W.J. Adams. 2020. Updated multiple linear regression (MLR) models for predicting chronic aluminum toxicity to freshwater aquatic organisms and developing water quality guidelines. Environ. Toxicol. Chem. 39: 1724-1736. PDF
83. Wood, C.M., M.D. McDonald, M. Grosell, D.R. Mount, W.J. Adams, B.H.K. Po, and K.V. Brix. 2020. The potential for salt toxicity: Can the trans-epithelial potential across the gill serve as a metric for major ion toxicity in fish? Aquatic. Toxic. 226: 105568. PDF
82. Brix, K.V., D.K. DeForest, L. Tear, W. Peijnenburg, A. Peters, E. Traudt, and R. Erickson. 2020. Development of empirical bioavailability models for metals. Environ. Toxicol. Chem. 39(1): 85-100. PDF
2019
81. De Boeck, G., C.M. Wood, K.V. Brix, A.K. Sinha, V. Matey, O.E. Johannsson, A. Bianchini, L. Bianchini, J.N. Maina, G.D. Kavembe, M.B. Papah, M. Kisipan, and R.O. Ojoo. 2019. Fasting in the ureotelic Lake Magadi tilapia, Alcolapia grahami, does not reduce its high metabolic demand, increasing its vulnerability to siltation events. Conser. Physiology. coz60. PDF
80. Esbaugh, A.J., K.V. Brix, and M. Grosell. 2019. Na+-K+-ATPase isoform switching in zebrafish during transition to dilute freshwater habitats. Phil. Proc. R. Soc. B. 286: 20190630. PDF
79. Jung, E.H., K.V. Brix, and C.J. Brauner. 2019. The effect of temperature acclimation on thermal tolerance, hypoxia tolerance and aerobic scope in two subspecies of sheepshead minnow; Cyprinodon variegatus variegatus and Cyprinodon variegatus hubbsi. Comp. Biochem. Physiol. A. 232: 28-33. PDF
78. Rudman, S.M., J.M. Goos, J.B. Burant, K.V. Brix, T.C. Gibbons, C.J. Brauner, and P.D. Jeyasingh. 2019. Ionome and elemental transport kinetics are shaped by parallel evolution in threespine stickleback. Ecol. Let. 22: 645-653. PDF Supplemental
77. Zimmer, A.M., K.V. Brix, and C.M. Wood. 2019. Regulation and mechanisms of Ca2+uptake in freshwater and seawater acclimated killifish, Fundulus heteroclitus. J. Comp. Physiol. B. 189: 47-60. PDF
76. Cremazy, A., K.V. Brix, and C.M. Wood. 2019. Using the biotic ligand model framework to investigate metal-metal interactions on the uptake of Ag, Cd, Cu, Ni, Pb, and Zin in the freshwater snail Lymnaea stagnalis. Sci. Tot. Environ. 647: 1611-1625. PDF
2018
75. Brix, K.V., C.J. Brauner, D. Schluter, and C.M. Wood. 2018. Pharmacological evidence that DAPI inhibits NHE2 in Fundulus heteroclitus acclimated to freshwater. Comp. Biochem. Physiol. 211C: 1-6. PDF
74. Cremazy, A., K.V. Brix, and C.M. Wood. 2018. Chronic toxicity of binary mixtures of six metals (Ag, Cu, Cd, Pb, Ni and Zn) to the great pond snail Lymnaea stagnalis. Environ. Sci. Tech. 52: 5979-5988. PDF
73. DeForest, D.K., K.V. Brix, L.M. Tear, and W.J. Adams. 2018. Multiple linear regression (MLR) models for predicting chronic aluminum toxicity to freshwater aquatic organisms and developing water quality guidelines. Environ. Toxicol. Chem. 37(1): 80-90. PDF
2017
72. Brix, K.V., M.S. Tellis, A. Cremazy, and C.M. Wood. 2017. Characterization of the effects of binary metal mixtures on short-term uptake of Cd, Pb, and Zn by rainbow trout. Aquat. Toxicol. 193: 217-227. PDF
71. DeForest, D.K., R.C. Santore, A.C. Ryan, B. Church, M.J. Chowdhury, and K.V. Brix. 2017. Development of biotic ligand model (BLM)-based freshwater aquatic life criteria for lead following U.S. EPA guidelines. Environ. Toxicol. Chem. 36(11): 2965-2973. PDF
70. DeForest, D.K., K.V. Brix, J. Elphick, C. Rickwood, A. deBruyn, L. Tear, G. Gilron, S. Hughes, and W.J. Adams. 2017. Development of waterborne selenium screening guidelines for freshwater systems. Environ. Toxicol. Chem. 36(9): 2503-2513. PDF
69. Brix, K.V., D.K. DeForest, L.M. Tear, M. Grosell, and W.J. Adams. 2017. Use of multiple linear regression models for setting water quality criteria for copper: a complementary approach to the biotic ligand model. Environ. Sci. Technol. 51: 5182-5192. PDF
68. Brix, K.V., C.E. Schlekat, and E.R. Garmin. 2017. The mechanisms of nickel toxicity in aquatic environments: An Adverse Outcome Pathway (AOP) analysis. Environ. Toxicol. Chem. 36(5): 1128-1137. PDF
67. Arbildua, J.J., G. Villavicencio, P. Urrestarazu, K.V. Brix, W.J. Adams, and P.H. Rodriguez. 2017. Effect of Fe (III) on Pseudokirchinella subcapitata at circumneutral pH in standard laboratory water tests is explained by nutrient sequestration. Environ. Toxicol. Chem. 36(4): 952-958. PDF
66. Bianchini, F., C.M. Wood, H.L. Bergman, O.E. Johannsson, P. Laurent, C. Chevalier, M.L. Kisipan, G.D. Kavembe, M.B. Papah, K.V. Brix, G. De Boeck, J.N. Maina, R.O. Ojoo, and A. Bianchini. 2017. Metabolism and antioxidant defense in the larval chironomid Tanytarsus minutipalpus: adaptation to extreme conditions of Lake Magadi. Biol. Open. 6: 83-91. PDF
65. Fulton, J., C.M.R. Lemoine, C. Bucking, K.V. Brix, P.J. Walsh, and M.D. McDonald. 2017. A waterborne signal from Gulf toadfish, Opsanus beta, prompts pulsatile urea excretion in conspecifics. Physiol. Behav. 171: 92-99. PDF
64. Shartau, R.B., K.V. Brix, and C.J. Brauner. 2017. Characterization of Na+transport to gain insight into the mechanisms of acid-base balance and ion regulation in white sturgeon (Acipenser transmontanus). Comp. Biochem. Physiol. 204A: 197-204. PDF
2016
63. Brix, K.V., M.S. Tellis, A. Cremazy, and C.M. Wood. 2016. Characterization of the effects of binary metal mixtures on short-term uptake of Ag, Cu, and Ni by rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 180: 236-246. PDF
62. Wood, C.M., K.V. Brix, G. DeBoeck, H. Bergmann, A. Bianchini, L.F. Bianchini, J.N. Maina, O.E. Johannsson, G.D. Kavembe, M.B. Papah, K.M. Letura, and R.O. Ojoo. 2016. Mammalian metabolic rates in the hottest fish on earth. Sci. Rep. 6: 29990. PDF
61. DeForest, D.K., S. Pargee, C. Claytor, S.P. Canton, and K.V. Brix. 2016. Biokinetic food chain modeling of waterborne selenium pulses into aquatic food chains: implications for water quality criteria. Integr. Environ. Assess. Manag. 12(2): 230-246. PDF
2015
60. Brix, K.V., A.J. Esbaugh, E.M. Mager, and M. Grosell. 2015. Comparative evaluation of Na+uptake in Cyprinodon variegatus variegatus (Lacepede) and Cyprinodon variegatus hubbsi (Carr) (Cyprionodontiformes, Teleostei): Evaluation of NHE function in high and low Na+freshwater. Comp. Biochem. Physiol. 185A: 115-124. PDF
59. Adams, W.J., D.K. DeForest, L.M. Tear, K. Payne, and K.V. Brix. 2015. Long-term monitoring of arsenic, selenium and other elements in Great Salt Lake (Utah, USA) surface water, brine shrimp, and brine flies. Environ. Monitor. Assess. 187: 118. PDF
2014
58. Niyogi, S., K.V. Brix, and M. Grosell. 2014. Effects of chronic waterborne nickel exposure on growth, ion homeostasis, acid-base baIance, and nickel uptake in freshwater pulmonate snail, Lymnaea stagnalis. Aquat. Toxicol. 150: 36-44. PDF
57. Nys, C., C.R. Janssen, E.M. Mager, A.J. Esbaugh, K.V. Brix, M. Grosell, W.A. Stubblefield, K. Holze, and K.A.C. De Schamphelaere. 2014. Development and validation of a biotic ligand model for predicting chronic toxicity of lead (Pb) to Ceriodaphnia dubia. Environ. Toxicol. Chem. 33(2): 394-403. PDF
2013
56. Scott, G.R. and K.V. Brix. 2013. Evolution of salinity tolerance from transcriptome to physiological system. Mol. Ecol. 22(14): 3656-3658. PDF
55. Cardwell, R.D., D.K. DeForest, K.V. Brix, and W.J. Adams. 2013. Critical evaluation of Cd, Cu, Ni, Pb, and Zn biomagnification in aquatic ecosystems. Rev. Environ. Contam. Toxicol. 226: 101-122. PDF
54. Brix, K.V. and M. Grosell. 2013. Characterization of Na+uptake in the endangered desert pupfish, Cyprinodon macularius. Conser. Physiol. 1: 1-8. PDF
53. Brix, K.V. and M. Grosell. 2013. Evaluation of pre- and post-zygotic mating barriers, hybrid fitness, and phylogenetic relationship between Cyprinodon variegatus variegatus and Cyprinodon variegatus hubbsi (Cyprinodontiformes, Teleostei). J. Evol. Biol. 26: 854-866. PDF
52. Esbaugh, A.J., E.M. Mager, K.V. Brix, R. Santore, and M. Grosell. 2013. Implications of pH manipulation methods for metal toxicity: not all acidic environments are created equal. Aquat. Toxicol. 130-131: 27-30. PDF
51. Munley, K.M., K.V. Brix, J. Panlilio, and M. Grosell. 2013. Growth inhibition in early life-stage tests predicts full life-cycle toxicity effects of lead in the freshwater pulmonate snail, Lymnaea stagnalis. Aquat. Toxicol. 128-129: 60-66. PDF
50. Brix, K.V., C.M. Wood, and M. Grosell. 2013. Measuring titratable alkalinity by single versus double endpoint titration: an evaluation in two Cyprinodont species and implications for characterizing net H+flux in aquatic organisms. Comp. Biochem. Physiol. 164A: 221-228. PDF
2012
49. Brix, K.V., P. Gillette, T.R. Capo, A. Pourmand, and M. Grosell. 2012. The effects of dietary silver on larval growth in the echinoderm Lytechinus variegatus. Arch. Environ. Contam. Toxicol. 63: 95-100. PDF
48. Brix, K.V.and M. Grosell. 2012. Comparative characterization of Na+transport in Cyprinodon variegatus variegatusand Cyprinodon variegatus hubbsi: A model species complex for studying teleost invasion of freshwater. J. Exp. Biol. 215: 1199-1209. PDF
47. Esbaugh, A.J., K.V. Brix, E.M. Mager, K. De Schamphelaere, and M. Grosell. 2012. Multi-linear regression analysis, preliminary biotic ligand modeling, and cross species comparison of the effects of water chemistry on chronic lead toxicity in invertebrates. Comp. Biochem. Physiol. 155C: 423-431. PDF
46. DeForest, D.K., C.E. Schlekat, K.V. Brix, and A. Fairbrother. 2012. Secondary poisoning risk assessment of terrestrial birds and mammals exposed to nickel. Integr. Environ. Assess. Manag. 8(1): 107-119. PDF
45. Brix, K.V., A.J. Esbaugh, K.M. Munley, and M. Grosell. 2012. Investigations into the mechanism of lead toxicity to the freshwater pulmonate snail, Lymnaea stagnalis. Aquat. Toxicol. 106-107: 147-156. PDF
Kevin V. Brix, Ph.D. 